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Learn More: Headache Center

Feverfew

Feverfew (Tanacetum parthenium) is an herb with proven effectiveness in decreasing migraine frequency.

  • Feverfew acts as both a serotonin antagonist (inhibits the inflammation of blood vessels that is associated with migraines) and a histamine antagonist (prevents the release of inflammatory substances that may be involved in migraine pain signaling).
  • This herb also inhibits the synthesis of prostaglandins, compounds implicated in inflammatory responses.
  • Feverfew may significantly reduce the nausea and vomiting that accompany migraine attacks.
  • Possible side effects of feverfew are gastrointestinal ulceration and withdrawal symptoms when its use is discontinued. Withdrawal symptoms may include sleep disturbances, headaches, and muscle pain.
  • Feverfew should not be used during pregnancy and nursing or by patients using blood-thinning(anticoagulant) medications.

Last reviewed on: May 2010
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