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References
RealAge experts used the following resources and primary research to build the Pain Relief Health Assessment. Find more valuable pain relief health information with RealAge Smart Search.

General Information
Alliance for Aging Research
American Pain Foundation
The Merck Manual
Primary Articles
ACPA Medications & Chronic Pain. Covington, E., American Chronic Pain Association 2006; 1-40.
An inflammatory cascade leading to hyperresistinemia in humans. Lehrke, M., Reilly, M., Millington, S., Iqbal, N., Rader, D., Lazar, M., PLoS Medicine 2004 Nov;1(2):e45.
COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression. Chandrasekharan, N., Dai, H., Turepu Roos, K., Evanson, N., Tomsik, J., Elton, T., Simmons, D., Proceedings of the National Academy of Sciences of the United States of America 2002 Oct 15;99(21):13926-31.
Integration of Behavioral and Relaxation Approaches Into the Treatment of Chronic Pain and Insomnia. National Institutes of Health Technology Assessment Conference Statement, October 16-18, 1995.
Non-steroidal anti-inflammatory drugs, including cyclo-oxygenase-2 inhibitors, in osteoarthritic knee pain: meta-analysis of randomised placebo controlled trials. Bjordal, J., Ljunggren, A., Klovning, A., Slordal, L., British Medical Journal 2004 Dec 4;329(7478):1317.

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