Procedures and Prescription Treatments – Topical Prescription Creams

The only topical agent approved by the U.S. Food and Drug Administration (FDA) to reduce the appearance of fine lines, age spots, uneven pigmentation, and other signs of photoaging is prescription tretinoin. It also helps treat acne.

Tretinoin is a derivative of vitamin A. It promotes the formation of healthy new skin in the dermis, revealing smoother, less blemished, more even-looking skin. It also lightens skin, thereby reducing the appearance of age spots and uneven skin pigmentation. Trade names of tretinoin include:

• Retin-A®
• Retin-A MICRO®
• Renova®
• Avita®

Similar medications containing active ingredients that also are derived from vitamin A include Tazorac® and Differin®.

These prescription creams come with benefits and risks that should be discussed with a healthcare provider. Some potential side effects of tretinoin treatment include redness, irritation, and increased sun sensitivity.